4-苄氧基-2-甲酰基苯硼酸 (含有数量不等的酸酐)

4-苄氧基-2-甲酰基苯硼酸 (含有数量不等的酸酐) - Names and Identifiers

Name	(4-benzyloxy-2-formyl)phenyl boronic acid
Synonyms	264-717-2 AKOS BRN-0180 4-Benzyloxy-2-forMylphenyl acid 4-BENZYLOXY-2-FORMYLPHENYLBORONIC ACID 4-Benzyloxy-2-formylphenylboronic acid (4-benzyloxy-2-formyl)phenyl boronic acid [4-(benzyloxy)-2-formylphenyl]boronic acid 3-BENZYLOXY-6-(DIHYDROXYBORONO)BENZALDEHYDE 4,4'-propane-1,3-diylbis(1-methylpiperidine) piperidine, 4,4'-(1,3-propanediyl)bis[1-methyl- 3-Benzyloxy-6-boronobenzaldehyde diethyl acetal Boronic acid, B-[2-formyl-4-(phenylmethoxy)phenyl]-
CAS	139962-97-3
EINECS	264-717-2
InChI	InChI=1/C14H13BO4/c16-9-12-8-13(6-7-14(12)15(17)18)19-10-11-4-2-1-3-5-11/h1-9,17-18H,10H2

4-苄氧基-2-甲酰基苯硼酸 (含有数量不等的酸酐) - Physico-chemical Properties

Molecular Formula	C14H13BO4
Molar Mass	256.06
Density	1.26g/cm³
Boling Point	490.2°C at 760 mmHg
Flash Point	250.3°C
Vapor Presure	2E-10mmHg at 25°C
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.599

4-苄氧基-2-甲酰基苯硼酸 (含有数量不等的酸酐) - Risk and Safety

Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R43 - May cause sensitization by skin contact R36 - Irritating to the eyes
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S36/37 - Wear suitable protective clothing and gloves.

4-苄氧基-2-甲酰基苯硼酸 (含有数量不等的酸酐) - Introduction

4-benzyloxy-2-aldehyde phenylboronic acid, chemical formula C14H13BO4, is an organic boron compound. The following is a description of the nature, use, formulation and safety information:

Nature:
-Appearance: 4-benzyloxy-2-aldehyde phenylboronic acid is a white to yellow solid.
-Melting point: about 150°C.
-Solubility: Soluble in some organic solvents such as dimethyl sulfoxide and ethanol.

Use:
-4-benzyloxy-2-aldehyde phenylboronic acid is commonly used as a reagent in organic synthesis and can participate in a series of reactions, such as the synthesis of phenyltolicone.
-It can also be used as a metal catalyst and catalyst precursor.

Preparation Method:
The preparation of 4-benzyloxy-2-aldehyde phenylboronic acid can be carried out by the following steps:
1. First, hydroquinone and benzaldehyde are subjected to a condensation reaction under hydrochloric acid conditions to produce benzyloxyphenol.
2. Next, benzyloxyphenol and triphenylphosphine (organic phosphorus compound) are subjected to a condensation reaction in the presence of copper chloride to produce 4-benzyloxyphenylboronic acid.
3. Finally, 4-benzyloxyphenylboronic acid is oxidized to 4-benzyloxy-2-aldehyde phenylboronic acid through an oxidation reaction.

Safety Information:
-4-benzyloxy-2-aldehyde phenylboronic acid has a certain irritation, please wear appropriate protective gloves and personal protective equipment such as glasses for operation.
-When storing and handling, please follow chemical safety procedures and keep away from ignition and oxidizing agents.
-In case of leakage or excessive inhalation, please ventilate in time or seek professional medical assistance.

Last Update：2024-04-10 22:29:15